Protein Family Synopsis
Family Overview
Special Analysis

metallo-dependent hydrolases superfamily - Overview - Protein Family Synopsis

(PDB: 1P6B)

Members
(human, all organisms)
23, 1832
Drug targets
(human, all organisms)
3, 4
Members with known 3D structures
(human, all organisms)
14, 73
Members with tested compounds
(human, all organisms)
8, 16
Members with active compounds (<100nM)
(human, all organisms)
6, 9
Members with mutations reported
(human, all organisms)
23, 23

Lineage


metallo-dependent hydrolases superfamily (23) *
ACMSD family (1)
+ Unclassified (1)
ACMSD
ATZ/TRZ family (1)
+ Unclassified (1)
GDA
Adenosine and AMP deaminases family (6)
+ Unclassified (5)
ADA
AMPD1
AMPD3
AMPD2
ADAL
+ ADGF subfamily (1)
ADA2
HutI family (1)
+ Unclassified (1)
AMDHD1
Hydantoinase/dihydropyrimidinase family (6)
+ Unclassified (6)
DPYSL4
DPYS
CRMP1
DPYSL3
DPYSL2
DPYSL5
NagA family (1)
+ Unclassified (1)
AMDHD2
Peptidase M19 family (3)
+ Unclassified (3)
DPEP1
DPEP2
DPEP3
Phosphotriesterase family (1)
+ Unclassified (1)
PTER
TatD-type hydrolase family (3)
+ Unclassified (3)
TATDN3
TATDN1
TATDN2