Protein Family Synopsis
Family Overview
Special Analysis

aldo/keto reductase family - Overview - Protein Family Synopsis

(PDB: 3V0S)

Members
(human, all organisms)
15, 250
Drug targets
(human, all organisms)
1, 1
Members with known 3D structures
(human, all organisms)
10, 43
Members with tested compounds
(human, all organisms)
7, 18
Members with active compounds (<100nM)
(human, all organisms)
7, 12
Members with mutations reported
(human, all organisms)
14, 14

Lineage


aldo/keto reductase family (15) *
+ Unclassified (11)
AKR1B15
AKR1B10
AKR1A1
AKR1B1
AKR1C4
AKR1C3
AKR1D1
AKR1C2
AKR1C1
AKR1C8P
AKR1E2
+ Aldo/keto reductase 2 subfamily (3)
AKR7A2
AKR7A3
AKR7L
+ Glutamate--cysteine ligase light chain subfamily (1)
GCLM