Protein Family Synopsis
Family Overview
Special Analysis

Receptor class 2A subfamily - Overview - Protein Family Synopsis

(PDB: 3PXH)

Members
(human, all organisms)
4, 17
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
4, 10
Members with tested compounds
(human, all organisms)
2, 3
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
3, 3

Lineage


protein-tyrosine phosphatase family (93)
+ Unclassified (8)
PTP4A3
EPM2A
PTP4A2
CDKN3
SSH2
SSH3
SSH1
PTP4A1
+ Non-receptor class 1 subfamily (2)
PTPN1
PTPN2
+ Non-receptor class 2 subfamily (2)
PTPN11
PTPN6
+ Non-receptor class 3 subfamily (1)
PTPN9
+ Non-receptor class 4 subfamily (3)
PTPN12
PTPN18
PTPN22
+ Non-receptor class CDC14 subfamily (3)
CDC14A
CDC14B
CDC14C
+ Non-receptor class PTPDC1 subfamily (1)
PTPDC1
+ Non-receptor class dual specificity subfamily (27)
DUPD1
DUSP1
DUSP10
DUSP11
DUSP12
DUSP13
DUSP13
DUSP14
DUSP15
DUSP16
DUSP18
DUSP19
DUSP2
DUSP21
DUSP22
DUSP23
DUSP26
DUSP27
DUSP28
DUSP3
DUSP4
DUSP5
DUSP6
DUSP7
DUSP8
DUSP9
PTPMT1
+ Non-receptor class myotubularin subfamily (15)
MTM1
MTMR1
MTMR10
MTMR11
MTMR12
MTMR14
MTMR2
MTMR3
MTMR4
MTMR6
MTMR7
MTMR8
MTMR9
SBF1
SBF2
+ Non-receptor class subfamily (11)
PTPN13
PTPN14
PTPN20
PTPN21
PTPN23
PTPN3
PTPN4
PTPN5
PTPN7
STYX
STYXL1
+ Receptor class 1/6 subfamily (1)
PTPRC
+ Receptor class 2A subfamily (4) *
PTPRD
PTPRF
PTPRQ
PTPRS
+ Receptor class 2B subfamily (4)
PTPRK
PTPRM
PTPRT
PTPRU
+ Receptor class 3 subfamily (4)
PTPRB
PTPRH
PTPRJ
PTPRO
+ Receptor class 4 subfamily (2)
PTPRA
PTPRE
+ Receptor class 5 subfamily (2)
PTPRG
PTPRZ1
+ Receptor class 7 subfamily (1)
PTPRR
+ Receptor class 8 subfamily (2)
PTPRN
PTPRN2