Protein Family Synopsis
Family Overview
Special Analysis

RAD3/XPD subfamily - Overview - Protein Family Synopsis

(PDB: 5FMF)

Members
(human, all organisms)
2, 35
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 4
Members with tested compounds
(human, all organisms)
0, 0
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
2, 2

Lineage


helicase family (23)
+ Unclassified (4)
DDX60L
DDX60
SUPV3L1
ASCC3
+ Dicer subfamily (1)
DICER1
+ PIF1 subfamily (1)
PIF1
+ RAD25/XPB subfamily (1)
ERCC3
+ RAD3/XPD subfamily (2) *
ERCC2
RTEL1
+ RLR subfamily (3)
DDX58
DHX58
IFIH1
+ RecQ subfamily (5)
BLM
RECQL
RECQL4
RECQL5
WRN
+ SKI2 subfamily (5)
HELQ
HFM1
MTREX
SKIV2L
SNRNP200
+ UvrD subfamily (1)
FBH1