Protein Family Synopsis
Family Overview
Special Analysis

Mitofusin subfamily - Overview - Protein Family Synopsis

(PDB: 2J68)

Members
(human, all organisms)
2, 14
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 3
Members with tested compounds
(human, all organisms)
0, 0
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
2, 2

Lineage


TRAFAC class dynamin-like GTPase superfamily (30)
Dynamin/Fzo/YdjA family (14)
+ Unclassified (8)
DNM1L
OPA1
MX1
MX2
DNM2
DNM1
SRL
DNM3
+ EHD subfamily (4)
EHD1
EHD2
EHD3
EHD4
+ Mitofusin subfamily (2) *
MFN1
MFN2
GB1/RHD3-type GTPase family (11)
+ GB1 subfamily (11)
ATL1
ATL2
ATL3
GBP1
GBP2
GBP3
GBP4
GBP5
GBP6
GBP7
RNF112
IRG family (3)
+ Unclassified (3)
IRGM
IRGC
IRGQ
Very large inducible GTPase (VLIG) family (2)
+ Unclassified (2)
GVINP1
URGCP