Protein Family Synopsis
Family Overview
Special Analysis

MHC class I family - Overview - Protein Family Synopsis

(PDB: 4IIQ)

Members
(human, all organisms)
85, 155
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
40, 52
Members with tested compounds
(human, all organisms)
1, 1
Members with active compounds (<100nM)
(human, all organisms)
1, 1
Members with mutations reported
(human, all organisms)
16, 16

Lineage


MHC class I family (85) *
+ Unclassified (83)
HLA-B
HLA-A
HLA-A
HLA-H
HLA-B
HLA-C
HLA-A
HLA-A
HLA-A
HLA-A
HLA-B
HLA-C
HLA-A
HLA-E
HLA-A
HLA-A
HLA-A
HLA-G
HLA-A
HLA-B
HLA-B
HLA-B
AZGP1
HLA-A
HLA-A
HLA-A
HLA-A
HLA-A
HLA-A
HLA-A
HLA-A
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-B
HLA-C
HLA-C
HLA-C
HLA-C
HLA-C
HLA-C
HLA-F
HLA-A
HLA-B
HLA-B
HLA-C
HLA-A
HLA-B
HLA-B
HLA-C
HLA-B
HLA-C
HLA-C
HFE
HLA-B
HLA-B
RAET1L
RAET1G
RAET1E
HLA-B
MR1
HLA-C
ULBP3
ULBP2
ULBP1
HLA-C
+ MIC subfamily (2)
MICA
MICB