Protein Family Synopsis
Family Overview
Special Analysis

Fos subfamily - Overview - Protein Family Synopsis

(PDB: 1FOS)

Members
(human, all organisms)
4, 42
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
2, 3
Members with tested compounds
(human, all organisms)
1, 1
Members with active compounds (<100nM)
(human, all organisms)
1, 1
Members with mutations reported
(human, all organisms)
4, 4

Lineage


bZIP family (54)
+ Unclassified (12)
CREB1
ATF7
XBP1
ATF4
DDIT3
NRL
CREB5
CREM
BATF
BATF2
BATF3
ATF5
+ ATF subfamily (13)
ATF1
ATF2
ATF3
ATF6
ATF6B
CREB3
CREB3L1
CREB3L2
CREB3L3
CREB3L4
CREBL2
CREBZF
JDP2
+ C/EBP subfamily (5)
CEBPA
CEBPB
CEBPD
CEBPE
CEBPG
+ CNC subfamily (6)
BACH1
BACH2
NFE2
NFE2L1
NFE2L2
NFE2L3
+ CREBRF subfamily (1)
CREBRF
+ Fos subfamily (4) *
FOS
FOSB
FOSL1
FOSL2
+ Jun subfamily (3)
JUN
JUNB
JUND
+ Maf subfamily (6)
MAF
MAFA
MAFB
MAFF
MAFG
MAFK
+ NFIL3 subfamily (1)
NFIL3
+ PAR subfamily (3)
DBP
HLF
TEF