Protein Family Synopsis
Family Overview
Special Analysis

FANCM sub-subfamily - Overview - Protein Family Synopsis

(PDB: 4DAY)

Members
(human, all organisms)
1, 28
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
1, 1
Members with tested compounds
(human, all organisms)
0, 1
Members with active compounds (<100nM)
(human, all organisms)
0, 0
Members with mutations reported
(human, all organisms)
1, 1

Lineage


DEAD box helicase family (60)
+ Unclassified (4)
DDX53
DDX28
DDX43
DDX25
+ DDX1 subfamily (1)
DDX1
+ DDX10/DBP4 subfamily (1)
DDX10
+ DDX18/HAS1 subfamily (1)
DDX18
+ DDX19/DBP5 subfamily (2)
DDX19A
DDX19B
+ DDX20 subfamily (1)
DDX20
+ DDX21/DDX50 subfamily (2)
DDX21
DDX50
+ DDX23/PRP28 subfamily (1)
DDX23
+ DDX24/MAK5 subfamily (1)
DDX24
+ DDX27/DRS1 subfamily (1)
DDX27
+ DDX3/DED1 subfamily (2)
DDX3X
DDX3Y
+ DDX31/DBP7 subfamily (1)
DDX31
+ DDX4/VASA subfamily (1)
DDX4
+ DDX41 subfamily (1)
DDX41
+ DDX42 subfamily (1)
DDX42
+ DDX46/PRP5 subfamily (1)
DDX46
+ DDX47/RRP3 subfamily (1)
DDX47
+ DDX49/DBP8 subfamily (1)
DDX49
+ DDX5/DBP2 subfamily (2)
DDX17
DDX5
+ DDX51/DBP6 subfamily (1)
DDX51
+ DDX52/ROK1 subfamily (1)
DDX52
+ DDX54/DBP10 subfamily (1)
DDX54
+ DDX55/SPB4 subfamily (1)
DDX55
+ DDX56/DBP9 subfamily (1)
DDX56
+ DDX59 subfamily (1)
DDX59
+ DDX6/DHH1 subfamily (1)
DDX6
+ DEAH subfamily (22)
BRIP1
DHX29
DHX30
DHX32
DHX33
DHX34
DHX35
DHX36
DHX37
DHX40
DHX57
DHX9
TDRD9
YTHDC2
+ DDX11/CHL1 sub-subfamily (3)
DDX11
DDX11L8
DDX12P
+ DDX15/PRP43 sub-subfamily (1)
DHX15
+ DDX16/PRP8 sub-subfamily (1)
DHX16
+ DDX8/PRP22 sub-subfamily (1)
DHX8
+ FANCM sub-subfamily (1) *
FANCM
+ PRP16 sub-subfamily (1)
DHX38
+ DECD subfamily (2)
DDX39A
DDX39B
+ eIF4A subfamily (3)
EIF4A1
EIF4A2
EIF4A3