Protein Family Synopsis
Family Overview
Special Analysis

Adenosine and AMP deaminases family - Overview - Protein Family Synopsis

(PDB: 2A3L)

Members
(human, all organisms)
6, 246
Drug targets
(human, all organisms)
1, 1
Members with known 3D structures
(human, all organisms)
3, 7
Members with tested compounds
(human, all organisms)
5, 9
Members with active compounds (<100nM)
(human, all organisms)
4, 6
Members with mutations reported
(human, all organisms)
6, 6

Lineage


metallo-dependent hydrolases superfamily (23)
ACMSD family (1)
+ Unclassified (1)
ACMSD
ATZ/TRZ family (1)
+ Unclassified (1)
GDA
Adenosine and AMP deaminases family (6) *
+ Unclassified (5)
ADA
AMPD1
AMPD3
AMPD2
ADAL
+ ADGF subfamily (1)
ADA2
HutI family (1)
+ Unclassified (1)
AMDHD1
Hydantoinase/dihydropyrimidinase family (6)
+ Unclassified (6)
DPYSL4
DPYS
CRMP1
DPYSL3
DPYSL2
DPYSL5
NagA family (1)
+ Unclassified (1)
AMDHD2
Peptidase M19 family (3)
+ Unclassified (3)
DPEP1
DPEP2
DPEP3
Phosphotriesterase family (1)
+ Unclassified (1)
PTER
TatD-type hydrolase family (3)
+ Unclassified (3)
TATDN3
TATDN1
TATDN2