Protein Family Synopsis
Family Overview
Special Analysis

ATM subfamily - Overview - Protein Family Synopsis

(PDB: 5NP0)

Members
(human, all organisms)
2, 36
Drug targets
(human, all organisms)
0, 0
Members with known 3D structures
(human, all organisms)
2, 4
Members with tested compounds
(human, all organisms)
2, 2
Members with active compounds (<100nM)
(human, all organisms)
2, 2
Members with mutations reported
(human, all organisms)
1, 1

Lineage


PI3/PI4-kinase family (20)
+ Unclassified (11)
PIK3CD
PIK3C2A
PIK3C2B
PIK3C2G
PIK3CA
PIK3CB
MTOR
PIK3CG
PRKDC
PIK3C3
SMG1
+ ATM subfamily (2) *
ATM
ATR
+ TRA1 subfamily (1)
TRRAP
+ Type II PI4K subfamily (2)
PI4K2A
PI4K2B
+ Type III PI4K subfamily (4)
PI4KA
PI4KAP1
PI4KAP2
PI4KB