Protein Family Synopsis
Family Overview
Special Analysis

ABC transporter superfamily - Overview - Protein Family Synopsis

(PDB: 2QSW)

Members
(human, all organisms)
49, 3999
Drug targets
(human, all organisms)
2, 2
Members with known 3D structures
(human, all organisms)
12, 72
Members with tested compounds
(human, all organisms)
17, 38
Members with active compounds (<100nM)
(human, all organisms)
7, 11
Members with mutations reported
(human, all organisms)
48, 48

Lineage


ABC transporter superfamily (49) *
+ Unclassified (1)
ABCA13
ABCA family (12)
+ Unclassified (12)
ABCA8
ABCA1
ABCA4
ABCA11P
ABCA12
ABCA9
ABCA7
ABCA6
ABCA10
ABCA5
ABCA3
ABCA2
ABCB family (11)
+ Heavy Metal importer (TC 3.A.1.210) subfamily (2)
ABCB6
ABCB7
+ MHC peptide exporter (TC 3.A.1.209) subfamily (3)
ABCB9
TAP1
TAP2
+ Mitochondrial peptide exporter (TC 3.A.1.212) subfamily (1)
ABCB10
+ Multidrug resistance exporter (TC 3.A.1.201) subfamily (5)
ABCB1
ABCB11
ABCB4
ABCB5
ABCB8
ABCC family (12)
+ CFTR transporter (TC 3.A.1.202) subfamily (1)
CFTR
+ Conjugate transporter (TC 3.A.1.208) subfamily (11)
ABCC1
ABCC10
ABCC11
ABCC12
ABCC2
ABCC3
ABCC4
ABCC5
ABCC6
ABCC8
ABCC9
ABCD family (4)
+ Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily (4)
ABCD1
ABCD2
ABCD3
ABCD4
ABCE family (1)
+ Unclassified (1)
ABCE1
ABCF family (3)
+ EF3 subfamily (3)
ABCF1
ABCF2
ABCF3
ABCG family (5)
+ Eye pigment precursor importer (TC 3.A.1.204) subfamily (5)
ABCG1
ABCG2
ABCG4
ABCG5
ABCG8