Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Gene Copy Number Variation
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SAR1B (Q9Y6B6) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_B 38.46 3.0E-21 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) RAB1A (P62820), (Q7DB50) HUMAN 4FME_F 38.46 1.0E-21 4.1Å GTP 2012-09-05
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) RAB1A (P62820), (Q7DB50) HUMAN 4FME_C 38.46 1.0E-21 4.1Å GTP 2012-09-05
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_E 38.46 3.0E-21 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5F_A 38.35 8.0E-22 2.02Å GTP 2005-08-16
ADP-ribosylation factor family (100%) (view alignment) SAR1 (P20606) SEC23 (P15303) BAKER'S YEAST 1M2O_B 60 9.0E-61 2.5Å GNP 2002-09-20
ADP-ribosylation factor family (100%) (view alignment) SAR1A (Q9NR31) - HUMAN 2GAO_B 89.95 2.0E-100 2Å GDP 2006-03-21
ADP-ribosylation factor family (69%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_G 38.46 4.0E-21 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) CYTH3 (O43739) HUMAN 4KAX_A 38.46 3.0E-21 1.85Å GTP 2013-08-14
ADP-ribosylation factor family (100%) (view alignment) SAR1 (P20606) SEC23 (P15303) BAKER'S YEAST 1M2O_D 60 9.0E-61 2.5Å GNP 2002-09-20
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) SPAG9 (O60271) HUMAN 2W83_A 38.46 3.0E-21 1.93Å GTP 2009-07-14
ADP-ribosylation factor family (73%) (view alignment) ARF6 (P62330), ASAP3 (Q8TDY4) - HUMAN 3LVR_E 38.69 4.0E-22 3.38Å GDP 2010-06-09
ADP-ribosylation factor family (92%) (view alignment) SAR1 (P20606) SEC31 (P38968), SEC23 (P15303) BAKER'S YEAST 2QTV_B 61.4 4.0E-56 2.5Å GNP 2008-01-15
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FA9_B 98.41 1.0E-107 2.5Å GDP 2006-09-05
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) - HUMAN 1E0S_A 38.35 8.0E-22 2.28Å GDP 2000-04-18
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5D_A 38.35 8.0E-22 1.8Å GTP 2005-08-16
ADP-ribosylation factor family (100%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_J 60 9.0E-61 23Å GNP 2013-09-18
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330), Cyth3 (O08967) - MOUSE, HUMAN 6BBP_A 38.35 4.0E-21 35Å GTP 4IP 2018-01-10
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FMX_A 98.42 6.0E-109 1.8Å GDP 2006-09-05
ADP-ribosylation factor family (100%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_K 60 9.0E-61 23Å GNP 2013-09-18
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330), Cyth3 (O08967) - MOUSE, HUMAN 6BBQ_A 38.35 4.0E-21 35Å GTP 4IP 2018-01-10
ADP-ribosylation factor family (69%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_E 38.46 4.0E-21 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (100%) (view alignment) SAR1A (Q9NR31) - HUMAN 2GAO_A 89.95 2.0E-100 2Å GDP 2006-03-21
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) ctxA (P01555) HUMAN 2A5G_A 38.35 2.0E-21 2.66Å GTP 2005-08-16
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 1F6B_B 98.99 7.0E-115 1.7Å GDP 2002-01-09
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FA9_A 98.41 1.0E-107 2.5Å GDP 2006-09-05
ADP-ribosylation factor family (69%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_C 38.46 4.0E-21 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) - HUMAN 3N5C_B 38.46 1.0E-21 1.82Å GDP 2010-08-18
ADP-ribosylation factor family (100%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 4BZI_B 60 9.0E-61 23Å GNP 2013-09-18
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) - HUMAN 2J5X_A 38.35 8.0E-22 2.8Å GSP 2006-09-21
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) - HUMAN 3N5C_A 38.46 1.0E-21 1.82Å GDP 2010-08-18
ADP-ribosylation factor family (73%) (view alignment) ARF6 (P62330), ASAP3 (Q8TDY4) - HUMAN 3LVQ_E 38.69 4.0E-22 3.38Å GDP 2010-06-09
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 2FMX_B 98.42 6.0E-109 1.8Å GDP 2006-09-05
ADP-ribosylation factor family (70%) (view alignment) ARF6 (P62330) - HUMAN 2J5X_B 38.35 8.0E-22 2.8Å GSP 2006-09-21
ADP-ribosylation factor family (69%) (view alignment) ARF6 (P62330) (Q7DB50) HUMAN 3PCR_B 38.46 1.0E-21 2.5Å GTP 2011-01-05
ADP-ribosylation factor family (69%) (view alignment) Arf6 (P62331) KIF23 (Q02241) MOUSE 3VHX_A 38.46 4.0E-21 2.8Å GTP 2012-05-16
ADP-ribosylation factor family (100%) (view alignment) SAR1B (Q9QVY3) - CHINESE HAMSTER 1F6B_A 98.99 7.0E-115 1.7Å GDP 2002-01-09
ADP-ribosylation factor family (92%) (view alignment) SAR1 (P20606) SEC23 (P15303), SEC24 (P40482) BAKER'S YEAST 6GNI_B 61.4 4.0E-56 4.9Å GNP 2018-10-17