DAGLA (Q9Y4D2) - Overview - Molecular Target Synopsis
DAGLA, Sn1-specific diacylglycerol lipase alpha
Enzyme Classification 3.1.1.-
Also Known as DGLA_HUMAN, DAGLA, C11orf11, KIAA0659, NSDDR
Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: DAGLA is active in the following subcellular-locations: cell membrane.
GO terms: DAGLA is active in the following subcellular-locations: integral component of postsynaptic membrane, plasma membrane, postsynaptic membrane, varicosity.