Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(Q9WXM1) - Overview - Molecular Target Synopsis

Protein


, L-Ala-D/L-Glu epimerase
Enzyme Classification 5.1.1.20
UniProt Q9WXM1

Also Known as AEEP_THEMA

Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of a broad range of other dipeptides; is most efficient with L-Ala-D/L-Phe, L-Ala-D/L-Tyr, and L-Ala-D/L-His.

3DES
CRYSTAL STRUCTURE OF DIPEPTIDE EPIMERASE FROM THERMOTOGA MARITIMA COMPLEXED WITH L-ALA-L-PHE DIPEPTIDE
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
345Q9WXM1-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
5 structures (32 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis