MINPP1 (Q9UNW1) - Overview - Molecular Target Synopsis
MINPP1, Multiple inositol polyphosphate phosphatase 1
Enzyme Classification 18.104.22.168
Also Known as MINP1_HUMAN, MINPP1, MIPP
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
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UniProt: MINPP1 is active in the following subcellular-locations: endoplasmic reticulum lumen.
GO terms: MINPP1 is active in the following subcellular-locations: endoplasmic reticulum, endoplasmic reticulum lumen, extracellular exosome.