Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

GABRQ (Q9UN88) - Domains And Structures - Molecular Target Synopsis

Click Here to View Molecular Target 3D Synopsis

Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
(view alignment) GABRG2 (P18507) GABRA1 (P14867), GABRA1 (P08219), GABRB3 (P28472) 6HUJ_C 38.72 4.0E-57 NAG
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUP_A 37.33 3.0E-52 NAG BMA MAN PIO
(view alignment) Gabra1 (P62813) Gabrb1 (P15431), Gabrg2 (P18508) 6DW1_A 37.33 7.0E-52 NAG ABU BMA MAN
(view alignment) GABRB2 (P47870) GABRG2 (P18507), GABRA1 (P14867) 6D6T_A 52.32 1.0E-94 Y01 NAG ABU BMA
(view alignment) GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUG_D 37.33 3.0E-52 NAG BMA MAN PIO
(view alignment) GABRG2 (P18507) GABRA1 (P14867), GABRA1 (P08219), GABRB3 (P28472) 6HUK_C 38.72 4.0E-57 NAG
(view alignment) GABRA1 (P14867) GABRB2 (P47870), GABRG2 (P18507) 6D6U_B 37.33 5.0E-52 Y01 NAG BMA MAN
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUO_B 51.99 5.0E-94 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAF_A 41.2 1.0E-61 NAG IVM
(view alignment) GLRA3 (O75311) - 5VDI_B 41.69 1.0E-61 IVM 7C6
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUP_E 51.99 5.0E-94 NAG ABU BMA MAN DZP
(view alignment) GLRA3 (O75311) - 5TIO_C 41.69 2.0E-61 NAG 7C6
(view alignment) GLRA3 (O75311) - 5TIN_B 41.69 1.0E-61 7C6
(view alignment) GLRA3 (O75311) - 5VDI_A 41.69 1.0E-61 IVM 7C6
(view alignment) Gabrb1 (P15431) Gabra1 (P62813), Gabrg2 (P18508) 6DW1_B 51.58 2.0E-94 NAG BMA
(view alignment) GLRA1 (P23415) - 2M6I_B 50 2.0E-17 -
(view alignment) GLRA3 (O75311) - 5VDI_E 41.69 1.0E-61 IVM 7C6
(view alignment) GLRA3 (O75311) - 5TIO_A 41.69 2.0E-61 7C6
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5OJM_D 47.49 2.0E-79 NAG BMA MAN
(view alignment) GABRB2 (P47870) GABRG2 (P18507), GABRA1 (P14867) 6D6U_C 52.32 1.0E-94 Y01 NAG ABU BMA
(view alignment) glra1 (O93430) - 3JAE_A 41.2 1.0E-61 NAG
(view alignment) glra1 (O93430) - 3JAE_B 41.2 1.0E-61 NAG
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867) 6I53_B 51.99 5.0E-94 NAG BMA MAN
(view alignment) GLRA3 (O75311) - 5TIO_B 41.69 2.0E-61 7C6
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUK_B 51.99 5.0E-94 NAG BMA MAN
(view alignment) GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUG_A 37.33 3.0E-52 NAG BMA MAN PIO
(view alignment) GABRG2 (P18507) GABRA1 (P14867), GABRB3 (P28472) 6I53_C 38.72 4.0E-57 NAG
(view alignment) GLRA1 (P23415) - 2M6I_C 50 2.0E-17 -
(view alignment) GLRA1 (P23415) - 2M6B_A 50 2.0E-17 -
(view alignment) glra1 (O93430) - 3JAE_E 41.2 1.0E-61 NAG
(view alignment) GLRA3 (O75311) - 5VDH_B 41.69 2.0E-61 IVM 7C6
(view alignment) GABRB3 (P28472) GABRA5 (P31644) 6A96_D 52.32 6.0E-94 NAG BMA MAN
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5O8F_E 47.49 3.0E-79 NAG BMA MAN P9N
(view alignment) GABRB3 (P28472) GABRA5 (P31644) 6A96_C 52.32 6.0E-94 NAG BMA MAN
(view alignment) GLRA3 (O75311) - 5CFB_E 41.69 2.0E-61 NAG SY9
(view alignment) GABRA1 (P14867) GABRG2 (P18507), GABRB3 (P28472) 6I53_D 37.33 3.0E-52 NAG POV BMA MAN PIO
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867) 6I53_E 51.99 5.0E-94 NAG POV BMA MAN
(view alignment) Gabrb1 (P15431) Gabra1 (P62813), Gabrg2 (P18508) 6DW1_E 51.58 2.0E-94 NAG BMA
(view alignment) GLRA1 (P23415) - 2M6I_A 50 2.0E-17 -
(view alignment) GLRA3 (O75311) - 5TIN_A 41.69 1.0E-61 7C6
(view alignment) GABRB3 (P28472) - 4COF_E 52.32 4.0E-94 NAG BMA BEN
(view alignment) GABRB2 (P47870) GABRG2 (P18507), GABRA1 (P14867) 6D6U_A 52.32 1.0E-94 Y01 NAG ABU BMA
(view alignment) GABRG2 (P18507) GABRB2 (P47870), GABRA1 (P14867) 6D6U_E 38.67 4.0E-57 Y01
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUK_D 37.33 3.0E-52 NAG BMA MAN PIO
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P08219) 6HUG_E 51.99 5.0E-94 NAG BMA MAN
(view alignment) GABRB3 (P28472) GABRA5 (P31644) 6A96_B 52.32 6.0E-94 NAG ABU BMA MAN
(view alignment) GABRA5 (P31644) GABRB3 (P28472) 6A96_A 35.4 4.0E-51 NAG BMA MAN
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUJ_D 37.33 3.0E-52 NAG ABU BMA MAN PIO
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUP_B 51.99 5.0E-94 NAG ABU BMA MAN DZP
(view alignment) GABRA1 (P14867) GABRB2 (P47870), GABRG2 (P18507) 6D6T_B 37.33 5.0E-52 Y01 NAG BMA MAN
(view alignment) GLRA3 (O75311) - 5VDH_A 41.69 2.0E-61 IVM 7C6
(view alignment) GLRA1 (P23415) - 2M6I_D 50 2.0E-17 -
(view alignment) GLRA3 (O75311) - 5TIO_E 41.69 2.0E-61 7C6
(view alignment) Gabrg2 (P18508) Gabrb1 (P15431), Gabra1 (P62813) 6DW1_D 38.72 3.0E-57 -
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUO_D 37.33 3.0E-52 08H NAG BMA PIO MAN
(view alignment) GABRA1 (P14867) GABRB2 (P47870), GABRG2 (P18507) 6D6U_D 37.33 5.0E-52 Y01 FYP NAG BMA MAN
(view alignment) Gabrb1 (P15431) Gabra1 (P62813), Gabrg2 (P18508) 6DW0_B 51.58 2.0E-94 NAG ABU BMA
(view alignment) glra1 (O93430) - 3JAE_D 41.2 1.0E-61 NAG
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5O8F_D 47.49 3.0E-79 NAG BMA MAN P9N
(view alignment) GLRA3 (O75311) - 5TIN_E 41.69 1.0E-61 7C6
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5OJM_C 47.49 2.0E-79 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAD_C 41.2 1.0E-61 NAG SY9
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5OJM_E 47.49 2.0E-79 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAD_D 41.2 1.0E-61 NAG SY9
(view alignment) Gabra1 (P62813) Gabrb1 (P15431), Gabrg2 (P18508) 6DW1_C 37.33 7.0E-52 NAG ABU BMA MAN
(view alignment) GLRA3 (O75311) - 5CFB_B 41.69 2.0E-61 NAG SY9
(view alignment) Gabrg2 (P18508) Gabrb1 (P15431), Gabra1 (P62813) 6DW0_D 38.72 3.0E-57 -
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUK_E 51.99 5.0E-94 NAG H0Z BMA MAN
(view alignment) glra1 (O93430) - 3JAD_E 41.2 1.0E-61 NAG SY9
(view alignment) GLRA3 (O75311) - 5TIO_D 41.69 2.0E-61 7C6
(view alignment) Gabrb1 (P15431) Gabra1 (P62813), Gabrg2 (P18508) 6DW0_E 51.58 2.0E-94 NAG BMA
(view alignment) glra1 (O93430) - 3JAD_B 41.2 1.0E-61 NAG SY9
(view alignment) GLRA1 (P23415) - 2M6I_E 50 2.0E-17 -
(view alignment) GABRG2 (P18507) GABRA1 (P14867), GABRA1 (P08219), GABRB3 (P28472) 6HUO_C 38.72 4.0E-57 NAG
(view alignment) GLRA3 (O75311) - 5VDH_C 41.69 2.0E-61 NAG IVM 7C6
(view alignment) GLRA3 (O75311) - 5TIN_D 41.69 1.0E-61 7C6
(view alignment) GABRG2 (P18507) GABRA1 (P14867), GABRA1 (P08219), GABRB3 (P28472) 6HUP_C 38.72 4.0E-57 NAG
(view alignment) GABRB3 (P28472) - 4COF_D 52.32 4.0E-94 NAG BMA BEN
(view alignment) glra1 (O93430) - 3JAF_E 41.2 1.0E-61 NAG IVM
(view alignment) GLRA3 (O75311) - 5CFB_A 41.69 2.0E-61 NAG SY9
(view alignment) GLRA3 (O75311) - 5VDH_D 41.69 2.0E-61 IVM 7C6
(view alignment) Gabra1 (P62813) Gabrb1 (P15431), Gabrg2 (P18508) 6DW0_A 37.33 7.0E-52 NAG ABU BMA MAN
(view alignment) GABRA1 (P14867) GABRG2 (P18507), GABRB3 (P28472) 6I53_A 37.33 3.0E-52 NAG POV BMA MAN PIO
(view alignment) GLRA3 (O75311) - 5CFB_C 41.69 2.0E-61 NAG SY9
(view alignment) GLRA3 (O75311) - 5VDH_E 41.69 2.0E-61 IVM 7C6
(view alignment) GABRB3 (P28472) - 4COF_A 52.32 4.0E-94 NAG BMA BEN
(view alignment) GABRB3 (P28472) GABRA5 (P31644) 6A96_E 52.32 6.0E-94 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAD_A 41.2 1.0E-61 NAG SY9
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUP_D 37.33 3.0E-52 NAG BMA PIO MAN DZP
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5OJM_B 47.49 2.0E-79 NAG BMA MAN
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUO_E 51.99 5.0E-94 NAG ABU BMA MAN
(view alignment) glra1 (O93430) - 3JAF_B 41.2 1.0E-61 NAG IVM
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUK_A 37.33 3.0E-52 NAG H0Z BMA PIO MAN
(view alignment) GLRA3 (O75311) - 5VDI_C 41.69 1.0E-61 IVM 7C6
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5O8F_B 47.49 3.0E-79 NAG BMA MAN P9N
(view alignment) GABRB2 (P47870) GABRG2 (P18507), GABRA1 (P14867) 6D6T_C 52.32 1.0E-94 NAG ABU BMA
(view alignment) glra1 (O93430) - 3JAF_D 41.2 1.0E-61 NAG IVM
(view alignment) GABRG2 (P18507) GABRB2 (P47870), GABRA1 (P14867) 6D6T_E 38.64 4.0E-53 NAG
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUJ_B 51.99 5.0E-94 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAE_C 41.2 1.0E-61 NAG
(view alignment) GLRA3 (O75311) - 5CFB_D 41.69 2.0E-61 NAG SY9
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUJ_A 37.33 3.0E-52 NAG ABU BMA MAN PIO RI5
(view alignment) GABRB3 (P28472) - 4COF_B 52.32 4.0E-94 NAG BMA BEN
(view alignment) GABRG2 (P18507) GABRA1 (P08219), GABRB3 (P28472) 6HUG_C 38.72 4.0E-57 NAG RI5
(view alignment) GLRA3 (O75311) - 5TIN_C 41.69 1.0E-61 7C6
(view alignment) GABRB3 (P28472) - 4COF_C 52.32 4.0E-94 NAG BMA BEN
(view alignment) GABRA1 (P14867), GABRA1 (P08219) GABRG2 (P18507), GABRB3 (P28472) 6HUO_A 37.33 3.0E-52 NAG ABU BMA PIO MAN
(view alignment) Gabra1 (P62813) Gabrb1 (P15431), Gabrg2 (P18508) 6DW0_C 37.33 7.0E-52 NAG BMA MAN
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5OJM_A 47.49 2.0E-79 NAG BMA MAN
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5O8F_A 47.49 3.0E-79 NAG BMA MAN
(view alignment) GABRA1 (P14867) GABRB2 (P47870), GABRG2 (P18507) 6D6T_D 37.33 5.0E-52 Y01 FYP NAG BMA MAN
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P14867), GABRA1 (P08219) 6HUJ_E 51.99 5.0E-94 NAG BMA MAN
(view alignment) GABRA5 (P31644), GABRB3 (P28472) - 5O8F_C 47.49 3.0E-79 NAG BMA MAN P9N
(view alignment) GLRA3 (O75311) - 5VDI_D 41.69 1.0E-61 IVM 7C6
(view alignment) GABRB3 (P28472) GABRG2 (P18507), GABRA1 (P08219) 6HUG_B 51.99 5.0E-94 NAG BMA MAN
(view alignment) glra1 (O93430) - 3JAF_C 41.2 1.0E-61 NAG IVM