RPS6KA6 (Q9UK32) - Overview - Molecular Target Synopsis
RPS6KA6, Ribosomal protein S6 kinase alpha-6
Enzyme Classification 22.214.171.124
Also Known as KS6A6_HUMAN, RPS6KA6, RSK4
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis. Forms a complex with MAPK3/ERK1 but not with MAPK9 or MAPK14 in serum-starved cells.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
UniProt: RPS6KA6 is active in the following subcellular-locations: cytoplasm, cytosol, nucleus.
GO terms: RPS6KA6 is active in the following subcellular-locations: cytosol, fibrillar center, mitochondrion, nucleolus, nucleoplasm, nucleus.