Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
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Ligand Efficiency Plot
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AFF4 (Q9UHB7) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_G 100 0 3Å - 2014-05-07
AF-4 proto-oncoprotein (5%) (view alignment) AFF4 (Q9UHB7) ELL2 (O00472) HUMAN 5JW9_A 100 0 2Å - 2017-02-08
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_H 100 0 2.94Å - 2013-03-13
AF-4 proto-oncoprotein (4%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), tat (P04608), CCNT1 (O60563) HUMAN 4OR5_E 100 0 2.8Å - 2014-04-16
AF-4 proto-oncoprotein (4%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), tat (P04608), CCNT1 (O60563) HUMAN 4OR5_J 100 0 2.8Å - 2014-04-16
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_G 100 0 2.94Å - 2013-03-13
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_C 100 0 3Å - 2014-05-07
AF-4 proto-oncoprotein (4%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), tat (P04608), CCNT1 (O60563) HUMAN 6CYT_C 100 0 3.5Å - 2018-12-12
AF-4 proto-oncoprotein (23%) (view alignment) AFF4 (Q9UHB7) - HUMAN 6R80_A 100 0 2.2Å - 2019-06-12
AF-4 proto-oncoprotein (4%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), tat (P69697), CCNT1 (O60563) HUMAN 5L1Z_C 100 0 5.28Å - 2016-10-26
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563), tat (P69698) HUMAN 4OGR_L 100 0 3Å - 2014-05-07
AF-4 proto-oncoprotein (7%) (view alignment) AFF4 (Q9UHB7) CDK9 (P50750), CCNT1 (O60563) HUMAN 4IMY_I 100 0 2.94Å - 2013-03-13