Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLC2A6 (Q9UGQ3) - Overview - Molecular Target Synopsis

Protein


SLC2A6, Solute carrier family 2, facilitated glucose transporter member 6
UniProt Q9UGQ3

Also Known as GTR6_HUMAN, SLC2A6, GLUT9

Facilitative glucose transporter; binds cytochalasin B with low affinity.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: SLC2A6 is active in the following subcellular-locations: cell membrane.
GO terms: SLC2A6 is active in the following subcellular-locations: integral component of plasma membrane, membrane, plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLC2A6 has gain in 0 cell-lines, loss in 1 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: 786_0, RPMI_8226, TK_10

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H226, NCI-H2369, COV318

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: HMEC, HUVEC, SK-N-SH

(see details)