Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

hisB (Q9S5G5) - Overview - Molecular Target Synopsis

Protein


hisB, Histidine biosynthesis bifunctional protein HisB
Enzyme Classification 3.1.3.15
UniProt Q9S5G5

Also Known as HIS7_ECO57, hisB


2FPR
CRYSTAL STRUCTURE THE N-TERMINAL DOMAIN OF E. COLI HISB. APO MG MODEL.
RCSB/PDB
Inspect Structure
See all 3D Structures for hisB

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
355Q9S5G5-1

Sub-cellular localization


UniProt: hisB is active in the following subcellular-locations: cytoplasm.
GO terms: hisB is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project hisB has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For hisB there are:
5 structures (10 chains) solved
2 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis

Screening and Chemistry


hisB has been screened with compounds ( bioactivities). (see details)