Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ugl (Q9RC92) - Overview - Molecular Target Synopsis

Protein


ugl, Unsaturated glucuronyl hydrolase
Enzyme Classification 3.2.1.179
UniProt Q9RC92

Also Known as UGL_BACGL, ugl

Catalyzes the hydrolysis of oligosaccharides with unsaturated glucuronyl residues at the non-reducing terminal, to a sugar or an amino sugar, and an unsaturated D-glucuronic acid (GlcA), which is nonenzymatically converted immediately to alpha-keto acid. Monomer.

2D5J
UNSATURATED GLUCURONYL HYDROLASE TRIGGERS HYDRATION OF VINYL ETHER GROUP BUT NOT OF GLYCOSIDIC BOND
RCSB/PDB
Inspect Structure
See all 3D Structures for ugl

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
377Q9RC92-1

Sub-cellular localization


UniProt: ugl is active in the following subcellular-locations: cytoplasm.
GO terms: ugl is active in the following subcellular-locations: cytoplasm.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ugl has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For ugl there are:
7 structures (12 chains) solved
3 are solved in complex with at least one small molecule ligand
1 are solved with an approved drug

ugl is solved in complex with the approved drug(s):

BGC/DEXTROSE (2FV0_A).

(see details)
Molecular Target 3D Synopsis