ACTR3B (Q9P1U1) - Overview - Molecular Target Synopsis
ACTR3B, Actin-related protein 3B
Also Known as ARP3B_HUMAN, ACTR3B, ARP11, ARP4
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
|330||ENSG00000133627||ENST00000537264, ENST00000397282||ENSP00000446157, ENSP00000380452||Q9P1U1-2|
UniProt: ACTR3B is active in the following subcellular-locations: cell projection, cytoplasm, cytoskeleton.
GO terms: ACTR3B is active in the following subcellular-locations: Arp2/3 protein complex, cell projection, cytoplasm, extracellular exosome.