Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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Gene Copy Number Variation
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Germline Genetics

TRPM5 (Q9NZQ8) - Domains And Structures - Molecular Target Synopsis

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Select a homology cutoff:
Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQR_D 45.58 0 3.2Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQR_A 45.58 0 3.2Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKV_B 38.08 0 4.3Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCL_C 44.49 0 3.54Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQR_C 45.58 0 3.2Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MJ2_B 39.13 0 6.36Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIZ_A 39.13 0 6.1Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKV_C 38.08 0 4.3Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MJ2_A 39.13 0 6.36Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKW_C 38.08 0 4.5Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKX_B 38.08 0 4.2Å AR6 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6D73_D 38.08 0 3.8Å - 2019-05-15
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCL_A 44.49 0 3.54Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCJ_C 44.49 0 3.14Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKW_D 38.08 0 4.5Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKV_D 38.08 0 4.3Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIZ_C 39.13 0 6.1Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6D73_C 38.08 0 3.8Å - 2019-05-15
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRK_D 37.91 0 3.8Å - 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRK_B 37.91 0 3.8Å - 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6D73_B 38.08 0 3.8Å - 2019-05-15
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQV_A 45.5 0 3.1Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MJ2_D 39.13 0 6.36Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRJ_D 37.93 0 3.3Å APR 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRK_C 37.91 0 3.8Å - 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQR_B 45.58 0 3.2Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCQ_A 44.49 0 3.25Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKX_D 38.08 0 4.2Å AR6 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIZ_D 39.13 0 6.1Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKX_C 38.08 0 4.2Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCL_B 44.49 0 3.54Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MJ2_C 39.13 0 6.36Å - 2018-12-12
Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BWI_C 46.68 0 3.7Å Y01 NAG 2018-12-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQV_D 45.5 0 3.1Å Y01 2017-12-20
Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BWI_D 46.68 0 3.7Å Y01 NAG 2018-12-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCQ_C 44.49 0 3.25Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCO_B 44.49 0 2.88Å ATP 2017-12-13
Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BWI_A 46.68 0 3.7Å Y01 NAG 2018-12-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 5WP6_B 45.5 0 3.8Å DVT 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQV_C 45.5 0 3.1Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKW_B 38.08 0 4.5Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIX_C 39.13 0 3.6Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 5WP6_D 45.5 0 3.8Å DVT 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKW_A 38.08 0 4.5Å - 2019-08-28
Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BWI_B 46.68 0 3.7Å Y01 NAG 2018-12-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIX_D 39.13 0 3.6Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCJ_B 44.49 0 3.14Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 6BQV_B 45.5 0 3.1Å Y01 2017-12-20
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRK_A 37.91 0 3.8Å - 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRJ_A 37.93 0 3.3Å APR 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIZ_B 39.13 0 6.1Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCO_D 44.49 0 2.88Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRJ_C 37.93 0 3.3Å APR 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCQ_B 44.49 0 3.25Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCJ_D 44.49 0 3.14Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCO_A 44.49 0 2.88Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCL_D 44.49 0 3.54Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCJ_A 44.49 0 3.14Å - 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIX_B 39.13 0 3.6Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKX_A 38.08 0 4.2Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 5WP6_C 45.5 0 3.8Å DVT 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6D73_A 38.08 0 3.8Å - 2019-05-15
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCQ_D 44.49 0 3.25Å ATP 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) - ZEBRAFISH 6PKV_A 38.08 0 4.3Å - 2019-08-28
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) trpm2 (A0A0R4IMY7) - ZEBRAFISH 6DRJ_B 37.93 0 3.3Å APR 2018-09-19
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM2 (O94759) - HUMAN 6MIX_A 39.13 0 3.6Å - 2018-12-12
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) TRPM4 (Q8TD43) - HUMAN 5WP6_A 45.5 0 3.8Å DVT 2017-12-13
SLOG in TRPM (100%), Ion transport protein (100%) (view alignment) Trpm4 (Q7TN37) - MOUSE 6BCO_C 44.49 0 2.88Å ATP 2017-12-13