SLCO1C1 (Q9NYB5) - Overview - Molecular Target Synopsis
SLCO1C1, Solute carrier organic anion transporter family member 1C1
Also Known as SO1C1_HUMAN, SLCO1C1, OATP14, OATP1C1, OATPF, SLC21A14
Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
|730||ENSG00000139155||ENST00000381552, ENST00000545604||ENSP00000370964, ENSP00000444149||Q9NYB5-3|
UniProt: SLCO1C1 is active in the following subcellular-locations: cell membrane.
GO terms: SLCO1C1 is active in the following subcellular-locations: integral component of plasma membrane, plasma membrane.