Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

OBP2A (Q9NY56) - Overview - Molecular Target Synopsis

Protein


OBP2A, Odorant-binding protein 2a
UniProt Q9NY56

Also Known as OBP2A_HUMAN, OBP2A

Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids. Monomer.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: OBP2A is active in the following subcellular-locations: secreted.
GO terms: OBP2A is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project OBP2A has gain in 0 cell-lines, loss in 1 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: COLO205, SNB_19, LOXIMVI

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: CHP-212, U266B1, Hs 746T

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

3D Structures


For OBP2A there are:
1 structures (2 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis