Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

FAM49B (Q9NUQ9) - Overview - Molecular Target Synopsis

Protein


FAM49B, Protein FAM49B
UniProt Q9NUQ9

Also Known as FA49B_HUMAN, FAM49B

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: FAM49B is active in the following subcellular-locations: membrane.
GO terms: FAM49B is active in the following subcellular-locations: cilium, extracellular exosome, extracellular region, membrane, platelet alpha granule lumen.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project FAM49B has gain in 34 cell-lines, loss in 1 cell-lines and no signal in 970 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SK_OV_3, RPMI_8226, MCF7

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H920, KPL-4, MKN-74

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: MCF-7, NHEK, HMEC

(see details)