Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

NRBP2 (Q9NSY0) - Overview - Molecular Target Synopsis

Protein


NRBP2, Nuclear receptor-binding protein 2
UniProt Q9NSY0

Also Known as NRBP2_HUMAN, NRBP2

May regulate apoptosis of neural progenitor cells during their differentiation.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: NRBP2 is active in the following subcellular-locations: cytoplasm.
GO terms: NRBP2 is active in the following subcellular-locations: cytoplasm, endomembrane system.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project NRBP2 has gain in 10 cell-lines, loss in 2 cell-lines and no signal in 993 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: BT_549, RXF_393, MALME_3M

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: G120, KURAMOCHI, SNU-216

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, IMR-90

(see details)