Molecular Target Synopsis
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Domains and Structures
Drugs and Clinical Candidates
Druggability
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Ligand Efficiency Plot
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DROSHA (Q9NRR4) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Ribonuclease-III-like (93%), Ribonuclease III domain (100%) (view alignment) rnc (Q9PM40) - 3O2R_C 35.24 2.0E-12 1.25Å - 2010-08-04
Ribonuclease-III-like (100%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (100%) (view alignment) DROSHA (Q9NRR4) DGCR8 (Q8WYQ5) HUMAN 5B16_A 100 0 3.2Å - 2016-02-03
Ribonuclease-III-like (91%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (99%) (view alignment) rnc (Q9X0I6) - 1O0W_A 37.86 3.0E-15 1.99Å - 2002-11-13
Ribonuclease-III-like (94%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (78%) (view alignment) rnc (P9WH03) - 2A11_A 37.61 2.0E-12 2.1Å - 2005-07-05
Ribonuclease-III-like (93%), Ribonuclease III domain (100%) (view alignment) rnc (Q9PM40) - 3O2R_A 35.24 2.0E-12 1.25Å - 2010-08-04
Ribonuclease-III-like (93%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (99%) (view alignment) rnc (Q9PM40) - 3N3W_B 35.24 2.0E-12 2.2Å - 2010-06-02
Ribonuclease-III-like (93%), Ribonuclease III domain (100%) (view alignment) rnc (Q9PM40) - 3O2R_B 35.24 2.0E-12 1.25Å MLZ 2010-08-04
Double-stranded RNA binding motif (100%) (view alignment) DROSHA (Q9NRR4) - HUMAN 2NA2_A 100 0 - 2016-12-21
Ribonuclease-III-like (93%), Ribonuclease III domain (100%) (view alignment) rnc (Q9PM40) - 3O2R_D 35.24 2.0E-12 1.25Å MLZ 2010-08-04
Double-stranded RNA binding motif (100%) (view alignment) DROSHA (Q9NRR4) - HUMAN 2KHX_A 100 0 - 2010-02-23
Ribonuclease-III-like (91%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (99%) (view alignment) rnc (Q9X0I6) - 1O0W_B 37.86 3.0E-15 1.99Å - 2002-11-13
Ribonuclease-III-like (93%), Ribonuclease III domain (100%), Double-stranded RNA binding motif (99%) (view alignment) rnc (Q9PM40) - 3N3W_A 35.24 2.0E-12 2.2Å - 2010-06-02