OLFML3 (Q9NRN5) - Overview - Molecular Target Synopsis
OLFML3, Olfactomedin-like protein 3
Also Known as OLFL3_HUMAN, OLFML3
Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
|386||ENSG00000116774||ENST00000369551, ENST00000393300||ENSP00000358564, ENSP00000376977||Q9NRN5-2|
UniProt: OLFML3 is active in the following subcellular-locations: secreted.
GO terms: OLFML3 is active in the following subcellular-locations: extracellular vesicle.