Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SDR39U1 (Q9NRG7) - Overview - Molecular Target Synopsis

Protein


SDR39U1, Epimerase family protein SDR39U1
Enzyme Classification 1.1.1.-
UniProt Q9NRG7

Also Known as D39U1_HUMAN, SDR39U1, C14orf124, HCDI

Putative NADP-dependent oxidoreductase.

4B4O
CRYSTAL STRUCTURE OF HUMAN EPIMERASE FAMILY PROTEIN SDR39U1 (ISOFORM2) WITH NADPH
RCSB/PDB
Inspect Structure
See all 3D Structures for SDR39U1

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


GO terms: SDR39U1 is active in the following subcellular-locations: nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SDR39U1 has gain in 3 cell-lines, loss in 1 cell-lines and no signal in 1001 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: OVCAR_5, NCI_H322M, MOLT_4

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H1581, NCI-H209, HCC33

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, A549

(see details)

3D Structures


For SDR39U1 there are:
1 structures (8 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis