Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

LUC7L (Q9NQ29) - Overview - Molecular Target Synopsis


LUC7L, Putative RNA-binding protein Luc7-like 1
UniProt Q9NQ29

Also Known as LUC7L_HUMAN, LUC7L, LUC7L1

May bind to RNA via its Arg/Ser-rich domain.

Isoforms / Transcripts (Protein Coding)

Sub-cellular localization

GO terms: LUC7L is active in the following subcellular-locations: U1 snRNP, U2-type prespliceosome.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project LUC7L has gain in 0 cell-lines, loss in 6 cell-lines and no signal in 999 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: NCI_ADR_RES, SF_295, OVCAR_8

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: NCI-H187, KELLY, SK-N-DZ

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, K562, MCF-7

(see details)

3D Structures

At greater than 50% identity similarity to LUC7L there are:
1 structures (1 chains) solved
0 are solved in complex with at least one small molecule ligand

(see details)
Molecular Target 3D Synopsis