Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

OBP2B (Q9NPH6) - Overview - Molecular Target Synopsis

Protein


OBP2B, Odorant-binding protein 2b
UniProt Q9NPH6

Also Known as OBP2B_HUMAN, OBP2B

Probably binds and transports small hydrophobic volatile molecules.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: OBP2B is active in the following subcellular-locations: secreted.
GO terms: OBP2B is active in the following subcellular-locations: extracellular region.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project OBP2B has gain in 0 cell-lines, loss in 1 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: KM12, RPMI_8226, HL_60

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: HCC1599, CAL-148, HCC1143

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

3D Structures


At greater than 75% identity similarity to OBP2B there are:
1 structures (2 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis