Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

BAG3 (Q9LYP4) - Overview - Molecular Target Synopsis

Protein


BAG3, BAG family molecular chaperone regulator 3
UniProt Q9LYP4

Also Known as BAG3_ARATH, BAG3

Co-chaperone that regulates diverse cellular pathways, such as programmed cell death and stress responses. Binds to the ATPase domain of HSP70/HSC70 chaperones (By similarity). Interacts with HSP70-1.

4HWF
CRYSTAL STRUCTURE OF ATBAG3
RCSB/PDB
Inspect Structure
See all 3D Structures for BAG3

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
303Q9LYP4-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project BAG3 has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For BAG3 there are:
1 structures (2 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis