Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

(Q9HM14) - Overview - Molecular Target Synopsis

Protein


, ATP-dependent DNA helicase Ta0057
Enzyme Classification 3.6.4.12
UniProt Q9HM14

Also Known as XPD_THEAC

ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA.

5H8W
XPD MECHANISM
RCSB/PDB
Inspect Structure
See all 3D Structures for

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
602Q9HM14-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For there are:
3 structures (3 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis