Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RNF121 (Q9H920) - Overview - Molecular Target Synopsis

Protein


RNF121, RING finger protein 121
UniProt Q9H920

Also Known as RN121_HUMAN, RNF121

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: RNF121 is active in the following subcellular-locations: membrane.
GO terms: RNF121 is active in the following subcellular-locations: endoplasmic reticulum membrane, Golgi membrane, integral component of membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RNF121 has gain in 13 cell-lines, loss in 0 cell-lines and no signal in 992 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SK_MEL_5, COLO205, OVCAR_5

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: EPLC-272H, BHY, OCI-M1

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HSMM, A549

(see details)