Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ACTL8 (Q9H568) - Overview - Molecular Target Synopsis

Protein


ACTL8, Actin-like protein 8
UniProt Q9H568

Also Known as ACTL8_HUMAN, ACTL8

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
366ENSG00000117148ENST00000375406ENSP00000364555Q9H568-1

Sub-cellular localization


UniProt: ACTL8 is active in the following subcellular-locations: cytoplasm, cytoskeleton.
GO terms: ACTL8 is active in the following subcellular-locations: cytoplasm, cytoskeleton.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ACTL8 has gain in 1 cell-lines, loss in 0 cell-lines and no signal in 1004 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: RPMI_8226, SK_MEL_2, OVCAR_5

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: VMRC-LCD, TYK-nu, A4/Fuk

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: HeLa-S3, SK-N-SH, NHLF

(see details)