Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Germline Genetics

PLK3 (Q9H4B4) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 4A4L_A 52.78 2.0E-88 939 TLA
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 4A4O_A 52.78 2.0E-88 664 TLA
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2V5Q_A 52.58 9.0E-89 -
Protein kinase domain (100%) (view alignment) CIPK24 (Q9LDI3) - 4D28_D 35.13 6.0E-43 -
Protein kinase domain (99%) (view alignment) PLK4 (O00444) - 3COK_A 41.73 1.0E-61 ANP
Protein kinase domain (100%) (view alignment) (Q6DRK7) Map205 (P23226) 4J7B_A 50.35 1.0E-88 -
Protein kinase domain (100%) (view alignment) (Q6DRK7) Map205 (P23226) 4J7B_D 50.35 1.0E-88 -
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DBC_A 51.25 3.0E-89 2FR
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 4J52_A 53.38 1.0E-87 1J3
Protein kinase domain (100%) (view alignment) PLK3 (Q9H4B4) - 4B6L_A 100 0 9ZP
POLO box duplicated region (94%) (view alignment) PLK2 (Q9NYY3) - 4XB0_B 44.33 7.0E-43 -
POLO box duplicated region (94%) (view alignment) PLK2 (Q9NYY3) - 4RS6_B 44.39 6.0E-45 -
Protein kinase domain (100%) (view alignment) PLK2 (Q9NYY3) - 4I6B_A 66.67 3.0E-121 11G
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2OU7_A 53.38 1.0E-87 ANP
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DB8_A 51.25 3.0E-89 1FR
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 3THB_A 53.38 1.0E-87 3TA
Protein kinase domain (100%) (view alignment) PLK2 (Q9NYY3) - 4I5M_A 66.67 3.0E-121 R78
Protein kinase domain (100%) (view alignment) CIPK24 (Q9LDI3) - 4D28_B 35.13 6.0E-43 -
Protein kinase domain (99%) (view alignment) PLK4 (O00444) - 3COK_B 41.73 1.0E-61 ANP
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3D5W_A 51.6 6.0E-90 ADP
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 5TA8_A 53.38 6.0E-88 79C
Protein kinase domain (99%) (view alignment) SNF1 (P06782) - 2FH9_A 35.2 4.0E-39 -
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DBF_A 51.25 5.0E-89 5FR
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2V5Q_B 52.58 9.0E-89 -
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3D5X_A 51.25 5.0E-89 KWT
Protein kinase domain (100%) (view alignment) (Q6DRK7) - 3D5U_A 51.6 6.0E-90 -
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DBE_A 51.25 5.0E-89 4FR
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DBD_A 51.25 3.0E-89 3FR
Protein kinase domain (98%) (view alignment) AURKC (Q9UQB9) INCENP (Q9NQS7) 6GR8_A 35.63 6.0E-40 F8Z
Protein kinase domain (99%) (view alignment) PLK4 (O00444) - 4JXF_A 41.73 2.0E-61 631
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 3KB7_A 52.78 2.0E-88 071 TLA
Protein kinase domain (100%) (view alignment) (Q6DRK7) - 3D5V_A 51.25 3.0E-89 -
Protein kinase domain (99%) (view alignment) SNF1 (P06782) - 3MN3_A 35.2 4.0E-39 -
Protein kinase domain (100%) (view alignment) CIPK24 (Q9LDI3) - 4D28_C 35.13 6.0E-43 -
POLO box duplicated region (94%) (view alignment) PLK2 (Q9NYY3) - 4XB0_A 44.33 7.0E-43 -
Protein kinase domain (100%) (view alignment) PLK2 (Q9NYY3) - 4I6F_A 66.67 3.0E-121 1C7
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 3FC2_A 53.38 1.0E-87 IBI
Protein kinase domain (100%) (view alignment) CIPK24 (Q9LDI3) - 4D28_A 35.13 6.0E-43 -
Protein kinase domain (100%) (view alignment) PLK2 (Q9NYY3) - 4I5P_A 66.67 3.0E-121 1D1
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 5TA6_A 53.38 6.0E-88 79D
Protein kinase domain (100%) (view alignment) (Q4KMI8) - 3DB6_A 51.25 5.0E-89 FRS
Protein kinase domain (98%) (view alignment) AURKC (Q9UQB9) INCENP (Q9NQS7) 6GR9_A 35.63 6.0E-40 VX6
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2RKU_A 53.38 1.0E-87 R78 TLA TAR
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2OWB_A 53.38 1.0E-87 626
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 4J53_A 53.38 1.0E-87 1J4
Protein kinase domain (100%) (view alignment) PLK1 (P53350) - 2YAC_A 52.78 2.0E-88 937 TLA
Protein kinase domain (99%) (view alignment) PLK4 (O00444) - 4YUR_A 41.73 1.0E-61 4J7
Protein kinase domain (100%) (view alignment) PLK2 (Q9NYY3) - 4I6H_A 66.67 3.0E-121 1C8
POLO box duplicated region (94%) (view alignment) PLK2 (Q9NYY3) - 4RS6_A 44.39 6.0E-45 -