Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ABHD16B (Q9H3Z7) - Overview - Molecular Target Synopsis

Protein


ABHD16B, Protein ABHD16B
Enzyme Classification 3.-.-.-
UniProt Q9H3Z7

Also Known as ABHGB_HUMAN, ABHD16B, C20orf135

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
487ENSG00000183260ENST00000369916ENSP00000358932
469Q9H3Z7-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project ABHD16B has gain in 7 cell-lines, loss in 1 cell-lines and no signal in 997 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: Hs 746T, NCI-H209, LN-18

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)


Screening and Chemistry


ABHD16B has been screened with compounds ( bioactivities). (see details)