Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

SLCO5A1 (Q9H2Y9) - Overview - Molecular Target Synopsis

Protein


SLCO5A1, Solute carrier organic anion transporter family member 5A1
UniProt Q9H2Y9

Also Known as SO5A1_HUMAN, SLCO5A1, OATP5A1, SLC21A15

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: SLCO5A1 is active in the following subcellular-locations: cell membrane.
GO terms: SLCO5A1 is active in the following subcellular-locations: integral component of plasma membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project SLCO5A1 has gain in 11 cell-lines, loss in 2 cell-lines and no signal in 992 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SK_MEL_5, U251, MCF7

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: TC-71, A-673, 928 mel

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: GM12878, SK-N-SH, NHLF

(see details)


Screening and Chemistry


SLCO5A1 has been screened with compounds ( bioactivities). (see details)