Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

ACTR6 (Q9GZN1) - Overview - Molecular Target Synopsis

Protein


ACTR6, Actin-related protein 6
UniProt Q9GZN1

Also Known as ARP6_HUMAN, ACTR6

Interacts with CBX1, CBX3 and CBX5.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


UniProt: ACTR6 is active in the following subcellular-locations: cytoplasm, cytoskeleton, nucleus.
GO terms: ACTR6 is active in the following subcellular-locations: cytoplasm, cytoskeleton, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project ACTR6 has gain in 1 cell-lines, loss in 1 cell-lines and no signal in 1003 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: MCF7, K_562, NCI_H460

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: KPL-4, SK-N-FI, UMC-11

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: NHLF, MCF-7, AG445

(see details)