KIN14E, Kinesin-like protein KIN-14E
Also Known as
KN14E_ARATH, KIN14E, KCBP, ZWI
Minus-end microtubule-dependent motor protein involved in the regulation of cell division and trichome morphogenesis through microtubules bundling. Possesses basal and microtubule-stimulated ATPase activities. Acts as a hub that brings together microtubules and actin filaments to modulate the cytoskeleton during trichome formation and morphogenesis (PubMed:26287478). Could be involved in the negative regulation of root growth (PubMed:25262228). Homodimer (via C-terminus) (PubMed:23805258). Binds microtubules via its N-terminus containing the MyTH4 domain and binds F-actin via its FERM domain (PubMed:26287478). Interacts with KIPK1 (PubMed:10788494, PubMed:25262228). Interacts with KIPK2 (PubMed:25262228). Interacts with AN (PubMed:11889034). Interacts with AIR9 (PubMed:25908862). Interacts (via C-terminus) with KIC, CAM2, CAM4 and CAM6. KIC and calmodulin show competitive binding to KCBP. Binding to calmodulin inhibits microtubule binding activity. Binding to KIC inhibits microtubule binding activity and microtubule-stimulated ATPase activity.