Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

STK31 (Q9BXU1) - Overview - Molecular Target Synopsis


STK31, Serine/threonine-protein kinase 31
Enzyme Classification
UniProt Q9BXU1

Also Known as STK31_HUMAN, STK31, SGK396

Isoforms / Transcripts (Protein Coding)

Sub-cellular localization

GO terms: STK31 is active in the following subcellular-locations: acrosomal vesicle, cytoplasm, nucleus.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project STK31 has gain in 6 cell-lines, loss in 1 cell-lines and no signal in 998 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: HCC_2998, KM12, DU_145

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: SNU-484, KMM-1, C2BBe1

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, NHLF, HSMM

(see details)

RNA Interference

STK31 was reported in the following RNAI studies:

Cell - Large Scale Profiling of Kinase Dependencies in Cancer Cell Lines, the highest RNAi cell lines are: 93VU, H23. (see details)

Screening and Chemistry

STK31 has been screened with 1 compounds (1 bioactivities). (see details)