Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

CDADC1 (Q9BWV3) - Overview - Molecular Target Synopsis


CDADC1, Cytidine and dCMP deaminase domain-containing protein 1
UniProt Q9BWV3

Also Known as CDAC1_HUMAN, CDADC1

May play an important role in testicular development and spermatogenesis.

Isoforms / Transcripts (Protein Coding)

Sub-cellular localization

GO terms: CDADC1 is active in the following subcellular-locations: cytoplasm, nucleus.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project CDADC1 has gain in 1 cell-lines, loss in 9 cell-lines and no signal in 995 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: SW_620, COLO205, BT_549

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: G111, NCI-H209, UACC-812

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HSMM, NHLF

(see details)

RNA Interference

CDADC1 was reported in the following RNAI studies:

Cell - Large Scale Profiling of Kinase Dependencies in Cancer Cell Lines, the highest RNAi cell lines are: DU4475, COV504. (see details)