Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

CDADC1 (Q9BWV3) - Overview - Molecular Target Synopsis

Protein


CDADC1, Cytidine and dCMP deaminase domain-containing protein 1
UniProt Q9BWV3

Also Known as CDAC1_HUMAN, CDADC1

May play an important role in testicular development and spermatogenesis.

Isoforms / Transcripts (Protein Coding)


Sub-cellular localization


GO terms: CDADC1 is active in the following subcellular-locations: cytoplasm, nucleus.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project CDADC1 has gain in 1 cell-lines, loss in 9 cell-lines and no signal in 995 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: SW_620, COLO205, BT_549

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: G111, NCI-H209, UACC-812

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: SK-N-SH, HSMM, NHLF

(see details)

RNA Interference


CDADC1 was reported in the following RNAI studies:

Cell - Large Scale Profiling of Kinase Dependencies in Cancer Cell Lines, the highest RNAi cell lines are: DU4475, COV504. (see details)