Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RTL8A (Q9BWD3) - Overview - Molecular Target Synopsis

Protein


RTL8A, Retrotransposon Gag-like protein 8A
UniProt Q9BWD3

Also Known as RTL8A_HUMAN, RTL8A, CXX1B, FAM127B, MAR8A

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
141ENSG00000203950ENST00000370775ENSP00000375267
113Q9BWD3-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project RTL8A has gain in 0 cell-lines, loss in 28 cell-lines and no signal in 977 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are:

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are:

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are:

(see details)

RNA Interference


RTL8A was reported in the following RNAI studies:

Cell - Large Scale Profiling of Kinase Dependencies in Cancer Cell Lines, the highest RNAi cell lines are: . (see details)