Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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Gene Copy Number Variation
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IFT27 (Q9BW83) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Ras family (98%) (view alignment) RAB10 (P61026) MICALCL (Q6ZW33) HUMAN 5SZJ_A 35.54 4.0E-20 2.66Å GNP 2016-08-24
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276) HUMAN 1TU3_C 37.13 6.0E-20 2.3Å GNP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6H_A 37.13 7.0E-20 1.51Å GNP 2002-11-27
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276) HUMAN 1TU3_E 37.13 6.0E-20 2.3Å GNP 2004-10-05
Ras family (100%) (view alignment) IFT27 (A8HN58) IFT25 (B8LIX8) GREEN ALGAE 2YC4_D 38.59 2.0E-30 2.8Å - 2011-03-23
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6N_A 36.53 3.0E-19 1.6Å GNP 2002-11-27
Ras family (100%) (view alignment) IFT27 (A8HN58) IFT25 (B8LIX8) GREEN ALGAE 2YC2_D 38.59 2.0E-30 1.59Å - 2011-03-23
Ras family (98%) (view alignment) RAB10 (P61026) MICAL1 (Q8TDZ2) HUMAN 5LPN_A 35.54 1.0E-20 2.8Å GNP 2016-08-24
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1TU4_A 37.13 6.0E-20 2.2Å GDP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1TU4_D 37.13 6.0E-20 2.2Å GDP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276), RABGEF1 (Q9UJ41) HUMAN 4Q9U_F 37.13 7.0E-20 4.6Å - 2014-07-23
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276) HUMAN 1TU3_A 37.13 6.0E-20 2.3Å GNP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) EEA1 (Q15075) HUMAN 3MJH_C 37.13 2.0E-19 1.95Å GTP 2010-05-05
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6P_A 36.53 3.0E-19 1.54Å GNP 2002-11-27
Ras family (100%) (view alignment) IFT27 (A8HN58) IFT25 (B8LIX8) GREEN ALGAE 2YC4_C 38.59 2.0E-30 2.8Å - 2011-03-23
Ras family (99%) (view alignment) RAB43 (Q86YS6) - HUMAN 2HUP_A 36.75 7.0E-20 2.05Å GDP 2006-08-08
Ras family (100%) (view alignment) RAB2B (Q8WUD1) - HUMAN 2A5J_A 35.33 9.0E-21 1.5Å GDP 2005-07-19
Ras family (99%) (view alignment) RAB5A (P20339) EEA1 (Q15075) HUMAN 3MJH_A 37.13 2.0E-19 1.95Å GTP 2010-05-05
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1TU4_B 37.13 6.0E-20 2.2Å GDP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276) HUMAN 1TU3_D 37.13 6.0E-20 2.3Å GNP 2004-10-05
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6O_A 36.53 2.0E-19 1.8Å GNP 2002-11-27
Ras family (98%) (view alignment) RAB10 (P61026) MICAL1 (Q8TDZ2) HUMAN 5LPN_C 35.54 1.0E-20 2.8Å GNP 2016-08-24
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276) HUMAN 1TU3_B 37.13 6.0E-20 2.3Å GNP 2004-10-05
Ras family (100%) (view alignment) IFT27 (A8HN58) IFT25 (B8LIX8) GREEN ALGAE 2YC2_C 38.59 2.0E-30 1.59Å - 2011-03-23
Ras family (99%) (view alignment) RAB5A (P20339) RABEP1 (Q15276), RABGEF1 (Q9UJ41) HUMAN 4Q9U_B 37.13 7.0E-20 4.6Å - 2014-07-23
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6R_A 36.53 3.0E-19 1.55Å GNP 2002-11-27
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1R2Q_A 37.13 7.0E-20 1.05Å GNP 2003-12-23
Ras family (98%) (view alignment) RAB30 (Q15771) - HUMAN 2EW1_A 38.89 8.0E-22 2Å GNP 2005-11-08
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6I_A 36.53 3.0E-19 1.6Å GDP 2002-11-27
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6L_A 36.53 3.0E-19 1.6Å GTP 2002-11-27
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1TU4_C 37.13 6.0E-20 2.2Å GDP 2004-10-05
Ras family (99%) (view alignment) RAB43 (Q86YS6) - HUMAN 2HUP_B 36.75 7.0E-20 2.05Å GDP 2006-08-08
Ras family (99%) (view alignment) RAB5A (P20339) - HUMAN 1N6K_A 36.53 3.0E-19 1.55Å GDP 2002-11-27