AIFM2 (Q9BRQ8) - Overview - Molecular Target Synopsis
AIFM2, Apoptosis-inducing factor 2
Enzyme Classification 1.-.-.-
Also Known as AIFM2_HUMAN, AIFM2, AMID, PRG3
Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
|Protein Length||Ensembl Gene||Ensembl Transcript||Ensembl Protein||Uniprot Isoform|
|373||ENSG00000042286||ENST00000307864, ENST00000373248||ENSP00000312370, ENSP00000362345||Q9BRQ8-1|
UniProt: AIFM2 is active in the following subcellular-locations: cytoplasm, membrane, mitochondrion outer membrane.
GO terms: AIFM2 is active in the following subcellular-locations: cytoplasm, cytosol, extracellular space, integral component of membrane, lipid droplet, mitochondrial outer membrane, mitochondrion.