Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
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Interaction Network
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Gene Copy Number Variation
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EIF2AK1 (Q9BQI3) - Domains And Structures - Molecular Target Synopsis

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Structural Sequence Similarity Matches
Domains Covered Gene Name (Uniprot) Solved in Complex with Organism PDB Chain Identity E-Value Resolution Ligands Release Date
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZY5_B 45.68 3.0E-15 2Å ANP 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_F 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZY4_A 45.68 3.0E-15 1.95Å - 2005-06-21
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7N_A 49.33 1.0E-14 2.35Å 3Z5 TLA 2015-01-28
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZY4_B 45.68 3.0E-15 1.95Å - 2005-06-21
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7O_A 49.33 1.0E-14 2.65Å 3Z6 2015-01-28
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYC_D 45.68 3.0E-15 3Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_A 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (88%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4G34_A 37.74 2.0E-14 2.7Å 924 2012-08-08
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_D 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYC_C 45.68 3.0E-15 3Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_E 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (89%) (view alignment) Eif2ak3 (Q9Z2B5) - MOUSE 3QD2_B 47.37 1.0E-14 2.8Å - 2011-04-27
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYD_B 45.68 3.0E-15 2.75Å ATP 2005-06-21
Protein kinase domain (88%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4M7I_A 37.74 2.0E-14 2.34Å 27D 2014-09-03
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7J_A 49.33 1.0E-14 2.3Å TLA 3Z1 2015-01-28
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYC_A 45.68 3.0E-15 3Å - 2005-06-21
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7K_A 49.33 1.0E-14 1.8Å TLA 3Z3 2015-01-28
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7H_A 49.33 1.0E-14 2Å 3Z2 2015-02-04
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYD_A 45.68 3.0E-15 2.75Å ATP 2005-06-21
Protein kinase domain (86%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4X7L_A 49.33 1.0E-14 1.9Å TLA 3Z4 2015-01-28
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_C 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZXE_B 45.68 3.0E-15 2.6Å - 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZY5_A 45.68 3.0E-15 2Å ANP 2005-06-21
Protein kinase domain (86%) (view alignment) GCN2 (P15442) - BAKER'S YEAST 1ZYC_B 45.68 3.0E-15 3Å - 2005-06-21
Protein kinase domain (88%) (view alignment) EIF2AK3 (Q9NZJ5) - HUMAN 4G31_A 37.74 2.0E-14 2.28Å 0WH 2012-08-08