Molecular Target Synopsis
Domains and Structures
Drugs and Clinical Candidates
Ligand Efficiency Plot
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
Germline Genetics

RASL11B (Q9BPW5) - Overview - Molecular Target Synopsis


RASL11B, Ras-like protein family member 11B
UniProt Q9BPW5

Also Known as RSLBB_HUMAN, RASL11B

Isoforms / Transcripts (Protein Coding)

Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform

Sub-cellular localization

GO terms: RASL11B is active in the following subcellular-locations: membrane.

GO terms

Gene Copy Number Variation

In COSMIC - Cell Lines Project RASL11B has gain in 4 cell-lines, loss in 4 cell-lines and no signal in 997 cell-lines. (see details)

Gene Expression

In NCI60, the highest expressing cell lines are: IGROV1, T47D, SK_MEL_2

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: DMS 79, NCI-H446, NCI-H510A

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: H1-hESC, SK-N-SH, HSMM

(see details)

3D Structures

At greater than 35% identity similarity to RASL11B there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand

(see details)
Molecular Target 3D Synopsis