Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

RASL11B (Q9BPW5) - Overview - Molecular Target Synopsis

Protein


RASL11B, Ras-like protein family member 11B
UniProt Q9BPW5

Also Known as RSLBB_HUMAN, RASL11B

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
248ENSG00000128045ENST00000248706ENSP00000248706Q9BPW5-1

Sub-cellular localization


GO terms: RASL11B is active in the following subcellular-locations: membrane.



UniProt
GO terms

Gene Copy Number Variation


In COSMIC - Cell Lines Project RASL11B has gain in 4 cell-lines, loss in 4 cell-lines and no signal in 997 cell-lines. (see details)

Gene Expression


In NCI60, the highest expressing cell lines are: IGROV1, T47D, SK_MEL_2

In Array Express (RNA-seq of 675 commonly used human cancer cell lines), the highest expressing cell lines are: DMS 79, NCI-H446, NCI-H510A

In Array Express (RNA-seq of long poly adenylated RNA and long non poly adenylated RNA from ENCODE cell lines), the highest expressing cell lines are: H1-hESC, SK-N-SH, HSMM

(see details)

3D Structures


At greater than 35% identity similarity to RASL11B there are:
1 structures (1 chains) solved
1 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis