Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
Mutations
Germline Genetics

mat (Q980S9) - Overview - Molecular Target Synopsis

Protein


mat, S-adenosylmethionine synthase
Enzyme Classification 2.5.1.6
UniProt Q980S9

Also Known as METK_SACS2, mat

Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

4WS9
CRYSTAL STRUCTURE OF SMAT N159G FROM SULFOLOBUS SOLFATARICUS
RCSB/PDB
Inspect Structure
See all 3D Structures for mat

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
404Q980S9-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project mat has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For mat there are:
5 structures (20 chains) solved
3 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis