Molecular Target Synopsis
Overview
Domains and Structures
Drugs and Clinical Candidates
Druggability
Chemistry
Ligand Efficiency Plot
Pathways
Family Cladogram
Interaction Network
Gene Expression
Gene Copy Number Variation
RNAi
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Germline Genetics

rpoL (Q980K0) - Overview - Molecular Target Synopsis

Protein


rpoL, DNA-directed RNA polymerase subunit L
Enzyme Classification 2.7.7.6
UniProt Q980K0

Also Known as RPOL_SACS2, rpoL

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

3HKZ
THE X-RAY CRYSTAL STRUCTURE OF RNA POLYMERASE FROM ARCHAEA
RCSB/PDB
Inspect Structure
See all 3D Structures for rpoL

Isoforms / Transcripts (Protein Coding)


Protein Length Ensembl Gene Ensembl Transcript Ensembl Protein Uniprot Isoform
92Q980K0-1

Gene Copy Number Variation


In COSMIC - Cell Lines Project rpoL has gain in 0 cell-lines, loss in 0 cell-lines and no signal in 0 cell-lines. (see details)

3D Structures


For rpoL there are:
3 structures (5 chains) solved
0 are solved in complex with at least one small molecule ligand



(see details)
Molecular Target 3D Synopsis